Human microbioma is the set of all the genomes of microorganisms located in the human body.
INDIVIDUAL GENETIC PROFILE:
Human gens + Microorganisms gens
This is why it is interesting to know the presence of these organisms, their genetic and involvement in our health.
Recent advances in molecular biology have allowed the development of a new science: metagenomics, a discipline that studies the different microbial communities in a given environment through DNA sequencing.
Studying the intestinal microbiome allows us know the status of the microbiota as an indicator of overall health through their metabolic, protective and nutritive functions.
Intestinal microbiota functions:
- Metabolic: Energy recovery in the form of fatty acids, vitamin production and favorable effects on the absorption of calcium and iron in the colon.
- Protective: Preventing the invasion of infectious agents or overgrowth of resident species with pathogenic potential.
- Nutritional or trophic: Proliferation and differentiation of the intestinal epithelium. Development and immune system modulation.
To deduce the absence or presence of intestinal dysbiosis and, depending on the detected pattern, help the clinician to detect certain associated diseases, such as allergies, diabetes type 2, obesity, celiac disease or inflammatory bowel disease, among others.
In case of diagnosis, it is extremely useful to measure the effectiveness of the administered drug (generally antibiotic or probiotic).