Genetic intolerance Lactose - Fructose

Price: 220 €

Turnaround time: 8 working days (monday to friday)

Echevarne Laboratory launches a test to detect genetic intolerance to lactose and fructose. This test is suitable for detecting lactose and/or fructose primary intolerance at a young age, once a baby begins to eat different types of food.

The activity of the lactase (the enzyme that metabolizes lactose) decreases with age, so that 75% of the adult population suffers intolerance to lactose (primary or genetic origin). This type of primary intolerance often occurs throughout life in certain ethnic groups and has a genetic cause. Those people notice as dairy products cause them more symptoms.

The hereditary fructose intolerance is a metabolic disease caused by mutations in the aldolase B gene (ALDOB). These mutations cause an accumulation of fructose and a decrease of glucose, essential for many cell functions. When a baby begins to eat fruit or vegetables, degrades sucrose and fructose and glucose release. If fructose can not be metabolized properly, it starts to accumulate in the cells, causing rapid intolerance symptoms such as vomiting, lethargy or dehydration.

This molecular screening extracts DNA from a blood sample and simultaneously provides the results of lactose and fructose intolerance. There are other tests, such as the breath test, which also detects intolerances from a secondary origin (result of a malfunctioning bowel), but they offer lower sensitivity and specificity, especially in children (between 5% and 20% error margin).