STRs analysis applied to Biotechnology allows authentication of any cell line or human biological material for use in the laboratory.
Historically it has been found that cell lines were used in laboratories in many cases misidentified due, for example, to cross-contamination. Recent studies claim that this happens yet, despite the existence of technology that allows univocal identification of any human biological material.
Due to its increasing both in research laboratories and biopharmaceutical industry importance, insist guides work on the recommendation of keeping track of the cell lines used, as well as identifying those biological materials used as therapeutic tools as a measure of traceability and product quality.
METHOD RECOMENDED BY ATCC® SDO
Echevarne Laboratory provides an identification tool with high capacity of discrimination:
Microsatellite analysis of DNA STRs
Microsatellite analysis of DNA STRsUsed for years in studies of individual identification and kinship because of their high capacity for discrimination between individuals.
- Maximum discrimination:
Analysis of 15 STR markers included in the international forensic guidelines for its high degree of discrimination. The identity probability ( probability that two randomly selected individuals have a genotype identical to that found ) of these 15 markers reaches values of 8x10 - 22 .
- Continuous traceability:
Identification, at any time of workflow, of crops and human samples, and prevent cross following materials multiple rounds of division or passing through various stages of production from a minimum amount of sample contamination.